Publications

Selected publications

Google scholar link HERE

H Laurent, DL Baker, AK Soper, ME Ries, L Dougan Bridging Structure, Dynamics, and Thermodynamics: An Example Study on Aqueous Potassium Halides, The Journal of Physical Chemistry B, 2021, 15, 11296 doi.org/10.1021/acs.jpcb.1c06728

MDH Hughes, BS Hanson, SE Cussons, N Mahmoudi, DJ Brockwell, L Dougan Control of Nanoscale in situ Protein Unfolding Defines Network Architecture and Mechanics of Protein Hydrogels, ACS Nano, 2021, 15, 11296 doi.org/10.1021/acsnano.1c00353

BS Hanson, L Dougan Intermediate Structural Hierarchy in Biological Networks Modulates the Fractal Dimension and Force Distribution of Percolating Clusters, Biomacromolecules, 2021 10, 4191  COVER FIGURE ARTICLE

H Laurent, DL Baker, AK Soper, ME Ries, L Dougan Solute Specific Perturbations to Water Structure and Dynamics in Tertiary Aqueous Solution, Journal Of Physical Chemistry B, 2020, 124: 10983 doi.org/10.1021/acs.jpcb.0c07780

A Aufderhorst-Roberts, MDG Hughes, A Hare, DA Head, N Kapur, DJ Brockwell L Dougan, Reaction Rate Governs the Viscoelasticity and Nanostructure of Folded Protein Hydrogels, Biomacromolecules, 2020, 21:4253 doi.org/10.1021/acs.biomac.0c01044

BS Hanson, L Dougan Network Growth and Structural Characteristics of Globular Protein Hydrogels, Macromolecules, 2020, 53: 7335 doi.org/10.1021/acs.macromol.0c00890

BS Hanson, C Brown, L Dougan Hierarchical Biomechanics: an introductory teaching framework, Physics Education 2020, 55:55022 DOI: https://doi.org/10.1088/1361-6552/ab9216

MDH Hughes, SE Cussons, N Mahmoudi, DJ Brockwell, L Dougan Single molecule protein stabilisation translates to macromolecular mechanics of protein network, Soft Matter, 2020, 16: 6389 DOI: 10.1039/C9SM02484K

H Laurent, AK Soper, L Dougan TMAO resists the compression of water structure by magnesium perchlorate: terrestrial kosmotrope vs. Martian chaotrope, PCCP, 2020, 22, 4924-4937 https://doi.org/10.1039/C9CP06324B

BS Hanson, C Brown, H Laurent, M Hughes, L Dougan Hierarchical Biomechanics: student engagement with a focus on biological physics, Physics Education 55 (2) , 25015, 2020
https://doi.org/10.1088/1361-6552/ab687e

BS Hanson, D Head, L Dougan The hierarchical emergence of worm-like chain behaviour from globular domain polymer chains Soft Matter 15 (43), 8778-8789, 2019
https://pubs.rsc.org/en/content/articlelanding/2019/SM/C9SM01656B#!divAbstract

H Laurent, AK Soper, L Dougan Biomolecular self-assembly under extreme Martian mimetic conditions Molecular Physics 117 (22), 3398-3407, 2019
doi.org/10.1080/00268976.2019.1649485

S Lenton, NH Rhys, JJ Towey, AK Soper, L Dougan Temperature-Dependent Segregation in Alcohol–Water Binary Mixtures Is Driven by Water Clustering The Journal of Physical Chemistry B 122, 7884-7894, 2018 doi.org/10.1021/acs.jpcb.8b03543

M Batchelor, M Wolny, M Kurzawa, L Dougan, PJ Knight, M Peckham Determining Stable Single Alpha Helical (SAH) Domain Properties by Circular Dichroism and Atomic Force Microscopy Molecular Motors 185-211 2018

Lenton S, Rhys NH, Towey JJ, Soper AK, Dougan L Highly compressed water structure observed in a perchlorate aqueous solution Nature Communications 8, 919-924, 2017
DOI:10.1038/s41467-017-01039-9

Wolny M, Batchelor M, Bartlett GJ, Baker EG, Kurzawa M, Knight PJ, Dougan L, Woolfson DN, Paci E, Peckham M Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability Scientific Reports 7, 44341, 2017
DOI:10.1038/srep44341

Alves da Silva M, Lenton S, Hughes M, Brockwell DJ, Dougan L Assessing the potential of folded globular polyproteins as hydrogel building blocks Biomacromolecules 18 636-646, 2017
DOI:10.1021/acs.biomac.6b01877

Tych KM, Batchelor M, Hoffmann T, Wilson MC, Hughes ML, Paci E, Brockwell DJ, Dougan L Differential effects of hydrophobic core packing residues for thermodynamic and mechanical stability of a hyperthermophilic protein. Langmuir : the ACS journal of surfaces and colloids 32 7392-7402, 2016
DOI:10.1021/acs.langmuir.6b01550

Lenton S, Walsh DL, Rhys NH, Soper AK, Dougan L Structural evidence for solvent-stabilisation by aspartic acid as a mechanism for halophilic protein stability in high salt concentrations. Physical Chemistry Chemical Physics 18 18054-18062, 2016
DOI:10.1039/c6cp02684b

Hughes ML, Dougan L The physics of pulling polyproteins: a review of single molecule force spectroscopy using the AFM to study protein unfolding. Reports on Progress in Physics 79 -, 2016
DOI:10.1088/0034-4885/79/7/076601

Towey JJ, Soper AK, Dougan L Low-Density Water Structure Observed in a Nanosegregated Cryoprotectant Solution at Low Temperatures from 285 to 238 K Journal of Physical Chemistry B 120 4439-4448, 2016
DOI:10.1021/acs.jpcb.6b01185