Publications

H Laurent, MDH Hughes, M Walko, DJ Brockwell, N Mahmoudi, TGA Youngs, TF Headen, L Dougan Visualisation of self-assembly and hydration of a beta-hairpin through integrated small and wide-angle neutron scattering, Biomacromolecules, 24(11), 4869 (2023)  doi.org/10.1021/acs.biomac.3c00583

MDH Hughes, SE Cussons, BS Hanson, KR Cook, T Feller, N Mahmoudi, DL Baker, R Ariens, DA Head, DJ Brockwell, L Dougan Building block aspect ratio controls assembly, architecture and mechanics of synthetic and natural protein networks, Nature Communications, 14(1), 5593 (2023)  doi.org/10.1038/s41467-023-40921-7

A Aufderhorst-Roberts, S Cussons, DJ Brockwell L Dougan, Diversity of viscoelastic properties of an engineered muscle-inspired protein hydrogel, Soft Matter, 2023, 19, 3167
DOI: 10.1039/D2SM01225A

K Cool, D Head, L Dougan, Modelling network formation by cluster aggregation kinetics, Soft Matter, 2023, 19, 2780
DOI: 10.1039/D3SM00111C

C Brown, M D G Hughes, D J Brockwell, N Mahmoudi, S Peyman, L Coletta, S Evans, L Dougan, Structural and mechanical properties of folded protein hydrogels with embedded microbubbles, Biomaterials Science, 2023, 11, 2726
DOI: 10.1039/D2BM01918C

H Laurent, TGA Youngs, TF Headen, AK Soper, L Dougan The ability of trimethylamine N-oxide to resist pressure induced perturbations to water structure, Communications Chemistry, 2022, 5, 1 doi.org/10.1038/s42004-022-00726-z

B.S. Hanson, L. Dougan, O.G. Harlen, S.A. Harris, D.J. Read A generalised mechano-kinetic model for use in multiscale simulation protocols doi.org/10.1101/2020.11.17.386524

M Nasralla, H Laurent, DL Baker, ME Ries, L Dougan A study of the interaction between TMAO and urea in water using NMR spectroscopy, Physical Chemistry Chemical Physics, 2022 doi.org/10.1021/acs.jpcb.1c06728

MDH Hughes, BS Hanson, SE Cussons, N Mahmoudi, DJ Brockwell, L Dougan Tuning Protein Hydrogel Mechanics through Modulation of Nanoscale Unfolding and Entanglement in Postgelation Relaxation, ACS Nano, 2022 doi.org/10.1021/acsnano.1c00353

C. Brown, K. Cook, P.A.Beales and L. Dougan SAWstitch: exploring self-avoiding walks through hand embroidery, Physics Education, 57, 4, 2022 doi.org/10.1088/1361-6552/ac6929

D. Kpeglo, M.D.G. Hughes, L. Dougan, M. Haddrick, M.A. Knowles, S. D.Evans and S.A.Peyman Modeling the Mechanical Stiffness of Pancreatic Ductal Adenocarcinoma, Matrix Biology Plus, 2022, 296 doi.org/10.1016/j.mbplus.2022.100109

H Laurent, DL Baker, AK Soper, ME Ries, L Dougan Bridging Structure, Dynamics, and Thermodynamics: An Example Study on Aqueous Potassium Halides, The Journal of Physical Chemistry B, 2021, 15, 11296 doi.org/10.1021/acs.jpcb.1c06728

MDH Hughes, BS Hanson, SE Cussons, N Mahmoudi, DJ Brockwell, L Dougan Control of Nanoscale in situ Protein Unfolding Defines Network Architecture and Mechanics of Protein Hydrogels, ACS Nano, 2021, 15, 11296 doi.org/10.1021/acsnano.1c00353

BS Hanson, L Dougan Intermediate Structural Hierarchy in Biological Networks Modulates the Fractal Dimension and Force Distribution of Percolating Clusters, Biomacromolecules, 2021 10, 4191 doi/10.1021/acs.biomac.1c00751

H Laurent, DL Baker, AK Soper, ME Ries, L Dougan Solute Specific Perturbations to Water Structure and Dynamics in Tertiary Aqueous Solution, Journal Of Physical Chemistry B, 2020, 124: 10983 doi.org/10.1021/acs.jpcb.0c07780

A Aufderhorst-Roberts, MDG Hughes, A Hare, DA Head, N Kapur, DJ Brockwell L Dougan, Reaction Rate Governs the Viscoelasticity and Nanostructure of Folded Protein Hydrogels, Biomacromolecules, 2020, 21:4253 doi.org/10.1021/acs.biomac.0c01044

BS Hanson, L Dougan Network Growth and Structural Characteristics of Globular Protein Hydrogels, Macromolecules, 2020, 53: 7335 doi.org/10.1021/acs.macromol.0c00890

BS Hanson, C Brown, L Dougan Hierarchical Biomechanics: an introductory teaching framework, Physics Education 2020, 55:55022 DOI: https://doi.org/10.1088/1361-6552/ab9216

MDH Hughes, SE Cussons, N Mahmoudi, DJ Brockwell, L Dougan Single molecule protein stabilisation translates to macromolecular mechanics of protein network, Soft Matter, 2020, 16: 6389 DOI: 10.1039/C9SM02484K